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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPB41L5 All Species: 8.48
Human Site: S420 Identified Species: 14.36
UniProt: Q9HCM4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCM4 NP_065960.2 733 81856 S420 S A L P V S P S I S S A P V P
Chimpanzee Pan troglodytes XP_001157953 733 81845 S420 S A L P V S P S I S S A P V P
Rhesus Macaque Macaca mulatta XP_001088764 726 81122 G410 N G S Q Q A W G M R S A L L V
Dog Lupus familis XP_532028 914 101864 W502 I H P S Q P R W H P H S P N V
Cat Felis silvestris
Mouse Mus musculus Q8BGS1 731 81617 S420 P V P V T S S S S C G A V Q V
Rat Rattus norvegicus Q5FVG2 731 81700 S420 P V P V T S F S S S G P V L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509941 820 90648 P420 T S P E L K E P E A E K M E L
Chicken Gallus gallus XP_422083 502 57358 T194 F R F V P T Q T E E M E L A I
Frog Xenopus laevis NP_001080234 498 57093 I190 L V S E F R F I P T Q S E E F
Zebra Danio Brachydanio rerio O57457 619 70690 K311 S L T R K L S K F S S L G S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650291 972 105216 P435 A A S Q S P A P A T P L V S S
Honey Bee Apis mellifera XP_623974 809 90976 D500 Q C S T K S S D S S V H P T P
Nematode Worm Caenorhab. elegans P28191 1026 115075 S581 S P R N S V A S Y S S F A S A
Sea Urchin Strong. purpuratus XP_788387 843 92835 P415 R T A I K T S P R V P P H P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.2 39.8 N.A. 83.9 83.6 N.A. 56.5 56.6 54.4 28.5 N.A. 36.8 38.9 24.3 39.1
Protein Similarity: 100 99.3 96.3 52.1 N.A. 89.2 88.4 N.A. 65.1 62.2 60.9 44.7 N.A. 51.8 53.1 40.1 56.7
P-Site Identity: 100 100 13.3 6.6 N.A. 20 20 N.A. 0 0 0 20 N.A. 6.6 26.6 26.6 6.6
P-Site Similarity: 100 100 40 13.3 N.A. 20 26.6 N.A. 26.6 13.3 13.3 20 N.A. 20 26.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 8 0 0 8 15 0 8 8 0 29 8 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 15 0 0 8 0 15 8 8 8 8 15 0 % E
% Phe: 8 0 8 0 8 0 15 0 8 0 0 8 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 8 0 0 15 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 8 0 8 8 8 0 0 % H
% Ile: 8 0 0 8 0 0 0 8 15 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 22 8 0 8 0 0 0 8 0 0 8 % K
% Leu: 8 8 15 0 8 8 0 0 0 0 0 15 15 15 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 8 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 15 8 29 15 8 15 15 22 8 8 15 15 29 8 29 % P
% Gln: 8 0 0 15 15 0 8 0 0 0 8 0 0 8 0 % Q
% Arg: 8 8 8 8 0 8 8 0 8 8 0 0 0 0 0 % R
% Ser: 29 8 29 8 15 36 29 36 22 43 36 15 0 22 8 % S
% Thr: 8 8 8 8 15 15 0 8 0 15 0 0 0 8 0 % T
% Val: 0 22 0 22 15 8 0 0 0 8 8 0 22 15 29 % V
% Trp: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _